久浪智醫 Anivance AI

The lung organ chip can reproduce the three-dimensional lung tissue structure including barrier, cilia, mucus, blood vessel layer, etc. Prof. Chen further combined the lung chip with a dynamic aerosol breathing system, automatic analysis and AI technology to create a human bionic lung system, which can be applied to toxicology and efficacy analysis of inhaled drugs.

肺器官晶片可重現包含屏障、纖毛、黏液、血管層等三維肺組織結構，並可在體外長期培養達60天以上，經比較慢性阻塞性肺病(COPD)患者肺晶片與健康者肺晶片的生理特性差異，發現與臨床相似度高達85%。陳冠宇進一步將肺晶片結合動態氣霧呼吸系統、自動化分析和AI技術打造出人體仿生肺系統，可運用於吸入性藥物的短中長期毒理與藥效分析。